Jun 1, 2009
Research on the cause and treatment of facioscapulohumeral muscular dystrophy (FSHD) might be entering a new, and hopefully better, era. For many years FSHD has been a difficult disease for medical researchers to study. In most genetic diseases, a gene with some known function is mutated and no longer performs its normal biological role. To find a treatment for such a disease, the medical researcher needs to identify therapeutic interventions that will compensate for the mutant gene.
Aug 8, 2008
Dr. Tapscott aims to use this grant to identify the potential mechanisms that cause FSHD, identifying the molecular changes that result from the FSHD mutation.
Aug 1, 2008
Dr. Kyba will insert D4Z4 repeats into the mouse genome in ES at a site on the X-chromosome, known to enable tissue-specific expression of transgenes, and to tolerate dominant lethal genes. He will study whether the presence of these repeats affects differentiation of the ES cells, and will produce mice bearing D4Z4 repeats, as a potential animal model for FSHD.
Jul 19, 2008
Friends of FSH Research in collaboration with the MDA fund a two-year grant for Dr. Joel Chamberlain.
Apr 15, 2008
$6.3 Million Dollar Grant for FSH Research — The Pathogenesis of FSHD.
Jan 16, 2008
Miller & Tapscott provide a first year summary of progress.
Aug 18, 2007
Seattle Time article on Friends of FSH Research