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MD CARE Amendments Act of 2013
Feb 25, 2013
Paul D. Wellstone Muscular Dystrophy Community Assistance, Research and Education (MD CARE) Amendments Act of 2013.
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Preventing DUX4 Activation and Apoptosis in FSHD Myotubes
Feb 20, 2013
By preventing DUX4 from being upregulated during muscle formation, we may be able to prevent further muscle wasting in patients with the disease.
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Identifying New Therapies
Feb 6, 2013
Using model organisms to identify new therapies and to understand the pathogenesis of FSHD.
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Deciphering transcription dysregulation in FSHD
Feb 6, 2013
New findings about DUX4 have raised as many fundamental questions about the molecular pathology of this unique disease as they have answered.
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Notice of Upcoming Funding Opportunity
Feb 6, 2013
Notice of Upcoming Funding Opportunity: Rare Disease Clinical Research Consortia.
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Michael Kyba Receives MDA Grant
Feb 6, 2013
Michael Kyba Receives MDA Grant to Study Muscle Developmental Deficits in FSHD.
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Progress Update: Using model organisms to identify new therapies and to understand the pathogenesis of facioscapulohumeral muscular dystrophy (FSHD)
Feb 6, 2013
Final progress update from FSH Scholar Barbara Page.
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RNA Interference as an investigative & therapeutic tool for FSHD: Update
Nov 28, 2012
The primary cause of FSHD is abnormal activation of the Dux4 gene, so mouse models need to reproduce production of Dux4.
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Progress Update: Mutations in genes that modify DNA packaging result in FSHD type 2
Nov 11, 2012
Friends of FSH Research has helped fund another ground breaking project that has shed new light on the mechanism of muscle damage in Facioscapulohumeral Muscular Dystrophy, and suggests new targets for treatment.
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Progress Update: Modulators of Epigenetic Disease
Oct 22, 2012
The milestones for year one were to perform an initial screen for Platform 1 and prepare and validate Platform 2.
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Development of anti-DUX4 therapeutics for FSHD
Sep 6, 2012
The chemicals Dr Kyba’s group has identified may help us to understand the chemical pathways that can indirectly inhibit the muscle toxicity associated with the DUX4 gene.
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Is a treatment for FSH near?
Aug 3, 2012
Today, we are very excited to report that the research team is working to find compounds that will impact DUX4 and allow FSH muscle cells to survive.
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Progress Update: Platform development and candidate drug screening for FSHD
Jul 24, 2012
The Miller Lab has made exciting progress in the development of a platform for screening genes and compounds with activities that affect FSHD-specific pathogenic processes.
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More MRI Studies
Jul 17, 2012
It would appear that the initial MRI study by Seth Friedman, Ph.D. and the subsequent longitudinal study now in progress has spurred interest in using MRI as a diagnostic tool for FSHD.
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Work for Cure, Love of Swimming Fuel Rick Colella
Jul 16, 2012
RICK Colella is happy to talk about the two world records he set last weekend at the U.S. Masters long course nationals, but the energy in his voice peaks when he starts discussing his role in eradicating a disease that affects a member of his family.
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DUX4-Regulated Genes Provide a Roadmap for FSHD Therapies
Jun 1, 2012
Analysis of the hundreds of genes regulated by the DUX4 transcription factor reveals a new understanding of the pathology of FSHD and may lead to tools that accelerate the development of therapies.
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Progress Update: Modulation of DUX4 Production
Apr 17, 2012
Asymmetric Bidirectional Transcription from the FSHD-Causing D4Z4 Array Modulates DUX4 Production
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Massage is promising for muscle recovery
Feb 12, 2012
Researchers at McMaster University have discovered a brief 10-minute massage helps reduce inflammation in muscle.
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Award winning photos of smooth muscle cells may help FSHD research
Feb 1, 2012
Stem cell researcher has become the first Australian to win microscopic image competition.
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Joel Chamberlain RNAi Update
Jan 15, 2012
Recent discoveries provide us with a clearer understanding of how the genetics of FSHD translate into disease.