Jan 31, 2014, 4:36 PM
Jong-Won Lim progress update.
Jan 30, 2014, 7:44 PM
An amazing turnout and show of support.
Jan 18, 2014, 7:36 PM
Dr. Kathryn Wagner provides a much needed tool.
Jan 17, 2014, 6:17 PM
Science joins Nature Publishing Group to Improve Reproducibility.
Jan 16, 2014, 6:06 PM
Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway.
Jan 13, 2014, 10:09 AM
Jan 8, 2014, 9:55 AM
The research goals of 2011-13 were to 1) create a model of FSHD that displayed features of the disease in muscles of laboratory mice through production of human DUX4 protein and 2) to test a therapeutic approach to block production of DUX4 protein in patient cell lines grown in tissue culture dishes in the laboratory.
Jan 7, 2014, 9:45 AM
We have developed a high-throughput screen based on the toxicity of DUX4 when overexpressed in C2C12 myoblasts, and identified inhibitors of DUX4-induced toxicity from within a diverse set of 44,000 small, drug-like molecules.