Search Results
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Progress Update: In vivo model to validate drugs targeting DUX4 enhancer/promoter activity
Mar 1, 2022, 11:22 AM
Dr. Hiramuki provides a final project update.
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Progress Update: SLC34A2 as a Biomarker for FSHD
Nov 13, 2021, 12:14 PM
Dr. Bloch provides a final report on progress.
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Progress Update: Screening of FDA-approved compounds
Jun 10, 2021, 10:01 AM
Dr. Lek provides a final update to her screening grant.
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Progress Update: SLC34A2 as a Biomarker for FSHD
Oct 14, 2020, 1:27 PM
Dr. Bloch provides an update on progress investigating a potential biomarker for FSHD.
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Progress Update: Screening of FDA-approved compounds
Oct 6, 2020, 11:43 AM
Dr. Lek provides an update on progress establishing a pipeline for testing the therapeutic potential of the drugs to reduce DUX4 toxicity, starting with everolimus.
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Progress Update: In vivo model to validate drugs targeting DUX4 enhancer/promoter activity
Mar 10, 2020, 1:46 PM
Latest progress from Yosuke Hiramuki.
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Progress Update: In vivo model to validate drugs targeting DUX4 enhancer/promoter activity
Oct 24, 2019, 4:35 PM
Yosuke Hiramuki provides an update on his novel mouse model.
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Progress Update: Xenograft Mouse Model
Jun 5, 2019, 12:32 PM
Dr. Bloch provides a final update on his xenograft mouse model project.
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Progress Update: A cell culture model of innate immunity for FSHD
Jul 31, 2018, 3:31 PM
Charles Emerson provides the final update on his recent study.
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Progress Update: 3rd Gen Oligonucleotide Targeting DUX4 in Mouse Model
Jul 11, 2018, 9:34 AM
Yi-Wen Chen DMV PhD provides an update on investigating 3rd generation oligonucleotides.
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Five New Grants Awarded
May 30, 2018, 10:18 AM
Exciting new research being funded both by your investments and through our co-funding partners.
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Pre-clinical Safety and Off-Target Studies to Support Translation of AAV-Mediated RNAi Therapy for FSHD
Jan 17, 2018, 9:47 PM
A publication from Scott Harper's lab reporting on the use of an AAV vector to test the safety of two miRNAs in silencing DUX4.
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Progress Update: 3rd Gen Oligonucleotide Targeting DUX4 in Mouse Model
Jan 1, 2018, 9:01 PM
Yi-Wen Chen DMV PhD provides an update on investigating 3rd generation oligonucleotides.
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Progress Update: Xenograft Mouse Model
Nov 15, 2017, 8:09 PM
Dr. Bloch provides a brief update of his progress on a xenograft mouse model.
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Progress Update: Xenotransplanation of Human Muscle
Jan 31, 2017, 1:11 PM
Update from Dr. Maura Parker on optimizing expansion of human muscle stem cells for transplant into mice.
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FSHD Animal Model Progress
Nov 28, 2016, 11:48 AM
SAB member Bruce Wentworth provides a brief update from the FSH Society Patient Connect Conference.
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Progress Update: FSHD myofibers cultured from human xenografts
Mar 24, 2016, 3:27 PM
Dr. Robert Bloch provides an update on his research into xenografting.
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Research funding: a collaborative effort to silence DUX4
Jul 11, 2015, 12:02 PM
An industry/academic collaboration to test a lead compound in a potentially robust animal model of FSHD.
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Research Funding: Dr. Bloch wants to get to the root of FSHD
May 3, 2015, 3:53 PM
Friends of FSH Research and FSHD Canada fund investigators at the University of Maryland.
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FSHD research progress highlighted at the Muscular Dystrophy Association Scientific Conference
Mar 17, 2015, 2:58 PM
FSHD was a hot topic at the MDA scientific conference in Washington D.C.
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Research Outlook 2015
Jan 20, 2015, 1:33 PM
Looking back on the research trends of 2014 helps us focus for the coming year.
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Research Funding: Dr. Maura Parker will improve cellular and animal models of FSHD
Jan 12, 2015, 1:25 PM
Dr. Parker has had her funding renewed based on approval of a progress report and submission of a new grant for the project's next steps that broadens the scope of impact of her work.
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Walking through Dr. Michael Kyba’s latest mouse model of FSHD
Sep 2, 2014, 8:40 AM
An in-depth analysis of the latest publication on a mouse model for FSHD. What does it mean? Why do we need a mouse model?
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Progress Update: Postnatal modeling of FSHD in mice
Jan 8, 2014, 9:55 AM
The research goals of 2011-13 were to 1) create a model of FSHD that displayed features of the disease in muscles of laboratory mice through production of human DUX4 protein and 2) to test a therapeutic approach to block production of DUX4 protein in patient cell lines grown in tissue culture dishes in the laboratory.