Search Results
#
Publication: Small noncoding RNAs in FSHD2 muscle cells reveal both DUX4- and SMCHD1-specific signatures
May 25, 2018, 9:34 AM
Identification of several types of small noncoding RNAs including known microRNAs that are differentially expressed in FSHD2 muscle cells compared to control.
#
Understanding FSHD2
Dec 19, 2014, 12:04 PM
Just in case FSH muscular dystrophy (FSHD) wasn’t confusing enough, now there’s a lot of talk about FSHD2. Let’s take some time to make sure we’re all on the same page and understand what’s going on.
#
Progress Update: Identification of small RNAs generated from the D4Z4 array by deep high-throughput sequencing
Aug 31, 2014, 2:57 PM
Drs. Filippova and Miller present their final results from the study.
#
Progress Update: Targeting Epigenetic Silencing of the 4qD4Z4 repeat array in FSHD
Jan 31, 2014, 4:36 PM
Jong-Won Lim progress update.
#
Progress Update: Mutations in genes that modify DNA packaging result in FSHD type 2
Nov 11, 2012, 1:03 PM
Friends of FSH Research has helped fund another ground breaking project that has shed new light on the mechanism of muscle damage in Facioscapulohumeral Muscular Dystrophy, and suggests new targets for treatment.
#
Common epigenetic changes of D4Z4 in contraction-dependent and contraction-independent FSHD
Jun 2, 2009, 1:58 PM
Facioscapulohumeral muscular dystrophy (FSHD), caused by partial deletion of the D4Z4 macrosatellite repeat on chromosome 4q, has a complex genetic and epigenetic etiology. To develop FSHD, D4Z4 contraction needs to occur on a specific genetic background. Only contractions associated with the 4qA161 haplotype cause FSHD.