Posted by Terry Elsas Colella on Oct 16, 2022
Friends of FSH Research is calling for grant proposals now for final submission by the end of January 2023 with funding in March 2023.
At this time we welcome any interested researcher to first submit a brief one to two paragraph summary of the scope of their project to ProgressReports@fshfriends.org. This will be reviewed by one or more members of our SAB, and may include queries for clarification. If the proposal aligns with our areas of interest, or is found to be a novel and potentially useful line of inquiry, then a full application will be requested for submission, as outlined on our website: Apply for a Grant. Before submitting your full proposal, please carefully read the requirements of a grant proposal.
The deadline for submission of initial summaries is 11:59 PM PT (Seattle) of 1-Dec-2022. The review process for such outlines is typically only a few days. On approval, the full proposal will be due by 11:59 PM PT (Seattle) of 31-Jan-2023. Funding decisions will be announced by mid-March 2023 after review by our SAB. Our areas of interest include:
- Biomarkers - Projects focused on FSHD biomarkers or methods of detection that will help determine the appropriate time to treat a patient with a therapeutic compound, test a patient's response to a therapeutic compound, or help elucidate disease, progression of disease or biomarker heterogeneity across a patient population. Of interest especially are imaging-based or inflammation-based biomarkers and studies that correlate molecular mechanisms, imaging biomarkers, pathology, and inflammation.
- Clinical Trial Support - Funding needs that help the development of a worldwide clinical trials network to support eventual approval of therapies aimed at treating or curing FSHD.
- FSHD Mechanism - Innovative pilot projects focused on developing our understanding of the initiation, progression, and ultimate destruction of muscle in FSHD patients.This includes projects that investigate DUX4 regulatory mechanisms in FSHD muscle, including transcription factors, epigenetic modifiers, regulatory networks, environmental activators, or other mechanisms. Also of interest are studies that investigate the short- and long-term effects of DUX4 expression and their contribution to the maintenance or progression of FSHD pathology.
- Ongoing Programs - Funding for an ongoing program which needs additional support to proceed or expand. This may include professional dedicated laboratory staff, outside contractors, administrative/program management support (directly related to research), consultants (e.g., regulatory advisors), equipment etc. Justification for this support must be provided and will be considered in terms of our mission.
- Novel Therapeutics - Seed funding for novel therapeutic approaches to treat FSHD.
- New Investigator and Trainee Support - Funding that supports innovative projects conducted by graduate students, postdoctoral fellows, early career investigators, or established investigators new to FSHD research, who may be interested in continuing FSHD research into the future
Among the various criteria, and depending on the subject of the grant, the Scientific Advisory Board typically reviews proposals based on:
- The design of the research
- Supporting preliminary data
- Other research support
- Past grant record with our organization, if any
- The capability of lab
- Willingness to share materials
Remember, initial summaries are due no later than 11:59 PM PT (Seattle) on Dec 1, 2022.
As noted above, to initiate the process with our Scientific Advisors, email ProgressReports@fshfriends.org.
Click here to view the full application instructions.
All applicants should be familiar with our institutional contract and confident of your institutional approval prior to submitting an application, and understand that additional contractual terms may apply depending on the nature of the project. Click here to download a copy of the institutional contract.
Funding level and timing can vary depending on needs of the project. Milestone-based payments may apply, depending on the request.
Finally, please share this information with colleagues who may be interested in FSHD research.