Sujatha Jagannathan PhD

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Assistant Professor


Department of Biochemistry and Molecular Genetics; RNA Bioscience Initiative University of Colorado, Anschutz Medical Campus

Dr. Jagannathan obtained her Ph. D. in Cell Biology from Duke University in 2013. She then moved to Seattle to pursue a postdoctoral fellowship in the laboratories of Drs. Stephen Tapscott and Robert Bradley. As an FSH Society postdoctoral fellow, Dr. Jagannathan studied the role of misregulated RNA quality control in FSHD pathogenesis. In January 2018, Dr. Jagannathan started her own research group at the University of Colorado Anschutz Medical Campus where she continues to study how RNA quality control contributes to muscle development and disease, with a focus on FSHD.

See also: http://www.jagannathan-lab.org

Grants Awarded
Validating cfDNA biomarker
Nov 1, 2024
Research - Basic
Build a prediction model based on subnucleosome signatures in cfDNA that (1) distinguishes the presence versus absence of FSHD in an individual, and (2) correlates with the active disease.
Deciphering the role of aberrant protein synthesis in FSHD
Feb 1, 2020
Research - Basic
When healthy muscle cells grown in the laboratory are forced to make the FSHD-causing protein DUX4, they die catastrophically. Studying these dying cells can offer a glimpse into the molecular events set in motion by DUX4 that culminate in cell death.
Deciphering the role of aberrant protein synthesis in FSHD
May 31, 2018
Research - Basic
Study the downstream consequences DUX4-mediated inhibition of an essential RNA quality control mechanism in the cell.