friends of FSH Research

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DUX4 Activates Germline Genes, Retroelements, and Immune Mediators

— December 28, 2011

DUX4 Activates Germline Genes, Retroelements, and Immune Mediators: Implications for Facioscapulohumeral Dystrophy.

Longitudinal Progression of Edema and Fatty Replacement of Lower Extremity Muscles in FSHD

— November 28, 2011

Degeneration of muscles in FHSD is associated with fatty replacement on magnetic resonance imaging.

Modulators of Epigenetic Disease

— November 27, 2011

Mechanism of Wnt Signaling in Facioscapulohumeral Muscular

— November 20, 2011

The gene thought to cause FSHD, Double Homeobox Protein 4 (DUX4), is unusual because it is encoded within each unit (D4Z4) of large arrays present on chromosomes 4 and 10.

MR Evaluation of Skeletal Muscles

— November 11, 2011

The main findings describe pervasive inflammation and heterogeneity of affected calf muscles in FSHD.